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RTOG 0915

SBRT

Peripheral - Peripheral Lung SBRT - 34 Gy/1 fx vs 48 Gy/4 fx

Dose Oracle
34 Gy / 1 fx(34 Gy/fx)BED₁₀ = 149.6 Gy• Single fraction (Arm 1)
PREFERRED48 Gy / 4 fx(12 Gy/fx)BED₁₀ = 105.6 Gy• 4-fraction regimen (Arm 2)

Indication

Peripheral Stage I NSCLC - comparing single fraction vs 4 fractions

Eligibility Criteria

  • Histologically confirmed NSCLC
  • T1-T2a N0 M0 (≤4cm)
  • Peripheral location (>2cm from mediastinum)
  • Medically inoperable
  • KPS ≥60

Staging

AJCC 7th edition T1-T2a N0 M0

Tags

SBRTLungPeripheralNSCLCSingle fraction4 fraction